Antibacterial-Resistant Pathogens Mechanisms of Transmission and Strategies for Prevention and Control

Antimicrobial-resistant pathogens’ transmission threatens the lives of patients. Microbial adaptation to the varied environment, mode of communication, the role of the microbiome in bacteria growth and development, gene expression, resistance selection and transmission between different environments as well as the metabolic reactions upshot spread of resistance. The communal presence of resistant pathogens aids their potential acquisition by wildlife and subsequent transfer to humans either directly or by contaminated foodstuffs. Mechanisms behind the antibiotic-induced conjugative spread of resistance plasmids in pathogens depend on genes and regulatory pathways that are involved in the enlarged frequency of resistance plasmids transfer caused by treatment with antimicrobial drugs. Antibiotic-induced conjugative spread resistance mechanisms aid microbes’ survival in an infection, promote their life cycle through replication and spread in host cells. Alteration of microbial physiology and cellular activities through metabolic modifications enhances fitness under varying conditions. This permits persistence and circulation between environments and also the nature of their pathogenesis.